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Re: CWD in Texas [Re: MoBettaHuntR] #5832914 07/15/15 04:12 PM
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Originally Posted By: MoBettaHuntR
I know this is technically off topic but for those believers here, yet another mystery mankind, science, common sense, and vast amounts of interpretation and data can't get a handle on. Like most problems in our country we cannot agree on. Sometimes there are factors outside of our control or understanding no matter how intelligent or redneck or otherwise we are. Not saying that CWD or other issues may never be explained just that sometimes God works in mysterious ways. That despite our beliefs may not be what we think or feel is happening or right.

I am also impressed with knowledge, concern, and relatively friendly banter that has gone on in this thread. There was a little name calling and back and forth. Ultimately I think anyone who read this thread is better educated. Lf, hf, dr, redneck, old money, new money, no money, we gotta get along to make progress, and the more debate, conversation and more minds at work the better.

In my opinion CWD remains a challenge and a concern. What is God's will in all of this... who knows?

As for the constant bending of our great country's Constitution on a regular basis these days I hope we all stand up against any injustice. Those who have been put in bad situation financially and otherwise by all of this I hope for the best and easiest remediation possible.

Thanks for all the good reading and shared knowledge. Keep up the good work THF.

This sentence illustrates to me the God factor in our world:

The propensity for trans-species prion transmission is related to the structural characteristics of the enciphering and heterologous PrP, but the exact mechanism remains mostly mysterious.

All the [/i]
si-entistfic [i]
lingo ends in the sentence just ends with it is really a mystery.


And that's exactly why it makes absolutely no logical sense to refuse the Pattersons offer to let them do research on this perfect sample. You don't solve mysteries by destroying your perfect sample population.


Crotchety old bastidge
Re: CWD in Texas [Re: therancher] #5833222 07/15/15 08:30 PM
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Originally Posted By: therancher
Originally Posted By: MoBettaHuntR
I know this is technically off topic but for those believers here, yet another mystery mankind, science, common sense, and vast amounts of interpretation and data can't get a handle on. Like most problems in our country we cannot agree on. Sometimes there are factors outside of our control or understanding no matter how intelligent or redneck or otherwise we are. Not saying that CWD or other issues may never be explained just that sometimes God works in mysterious ways. That despite our beliefs may not be what we think or feel is happening or right.

I am also impressed with knowledge, concern, and relatively friendly banter that has gone on in this thread. There was a little name calling and back and forth. Ultimately I think anyone who read this thread is better educated. Lf, hf, dr, redneck, old money, new money, no money, we gotta get along to make progress, and the more debate, conversation and more minds at work the better.

In my opinion CWD remains a challenge and a concern. What is God's will in all of this... who knows?

As for the constant bending of our great country's Constitution on a regular basis these days I hope we all stand up against any injustice. Those who have been put in bad situation financially and otherwise by all of this I hope for the best and easiest remediation possible.

Thanks for all the good reading and shared knowledge. Keep up the good work THF.

This sentence illustrates to me the God factor in our world:

The propensity for trans-species prion transmission is related to the structural characteristics of the enciphering and heterologous PrP, but the exact mechanism remains mostly mysterious.

All the [/i]
si-entistfic [i]
lingo ends in the sentence just ends with it is really a mystery.


And that's exactly why it makes absolutely no logical sense to refuse the Pattersons offer to let them do research on this perfect sample. You don't solve mysteries by destroying your perfect sample population.


Well said. cheers


Marc C. Helfrich
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Re: CWD in Texas [Re: Frio County Hunts] #5833409 07/15/15 10:55 PM
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Decision day is tomorrow in Austin. Should be interesting either way.

Re: CWD in Texas [Re: MoBettaHuntR] #5833444 07/15/15 11:21 PM
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Great post

Last edited by jmh004; 07/15/15 11:26 PM.
Re: CWD in Texas [Re: Frio County Hunts] #5833575 07/16/15 01:24 AM
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Very interesting read....
THE SKY IS NOT FALLING


Are idiots multiplying faster than normal people?[Linked Image]
Re: CWD in Texas [Re: Frio County Hunts] #5833705 07/16/15 03:11 AM
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Well this is from that guy, that according to some, has decimated the deer in Wisconsin. So what can we really get from this?

Re: CWD in Texas [Re: stxranchman] #5833742 07/16/15 03:51 AM
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Originally Posted By: stxranchman
Very interesting read....
THE SKY IS NOT FALLING


up Common Sense .. a breath of fresh air....

Last edited by SheepHunter; 07/16/15 03:53 AM.

Lucky 7 Exotic Ranch located in Eden, Tx. Well managed self sustaining herds roaming our 3,000 acre ranch. First Class Lodging, Ranch style meals and qualified guides. 30+ species.
Re: CWD in Texas [Re: Frio County Hunts] #5833752 07/16/15 03:59 AM
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I quit reading at "gorilla war"

Re: CWD in Texas [Re: LuckyHunter] #5833818 07/16/15 05:12 AM
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Originally Posted By: SheepHunter
Originally Posted By: stxranchman
Very interesting read....
THE SKY IS NOT FALLING


up Common Sense .. a breath of fresh air....


cheers texas


Marc C. Helfrich
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Re: CWD in Texas [Re: spitfire] #5834123 07/16/15 02:24 PM
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Originally Posted By: spitfire
I quit reading at "gorilla war"


I don't let spelling errors keep me from learning.


Crotchety old bastidge
Re: CWD in Texas [Re: therancher] #5834126 07/16/15 02:26 PM
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This has some very interesting and pertinent info.

https://m.youtube.com/watch?v=1_ltc3dNsPk&feature=youtu.be


Crotchety old bastidge
Re: CWD in Texas [Re: therancher] #5834144 07/16/15 02:34 PM
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Originally Posted By: therancher
Originally Posted By: spitfire
I quit reading at "gorilla war"


I don't let spelling errors keep me from learning.



Re: CWD in Texas [Re: Frio County Hunts] #5834437 07/16/15 05:32 PM
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Rare report of deer disease in Texas causes stir

Houston Chronicle

Rare report of deer disease in Texas causes stir, especially since it’s the 8 case of CWD documented in Texas, and the first case of CWD in Captive deer.

here is how I would have titled this article, and why.

Shannon Tompkins Finally Breaks Silence on Texas First Captive CWD Case and Starts Off Spreading False Information About Risk Factors. ...

Thursday, July 16, 2015

http://chronic-wasting-disease.blogspot.com/2015/07/rare-report-of-deer-disease-in-texas.html

Re: CWD in Texas [Re: Frio County Hunts] #5834529 07/16/15 06:17 PM
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So are you saying CWD is not rare in Texas? I would think one positive test out of who knows how many deer is pretty rare. These links that you post are always hard to follow. They don't seem to have a sense of direction. Just FYI, not trying to start anything.

Last edited by jmh004; 07/16/15 06:19 PM.
Re: CWD in Texas [Re: Frio County Hunts] #5834534 07/16/15 06:19 PM
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This is a little far afield of CWD, but it shows that a monoclonal antibody, can stop a folded protein (prion) disease in its tracks. http://www.medpagetoday.com/Neurology/GeneralNeurology/52625 All the more reason to do as much research as possible.


for every stereotype there's a prototype don't be the prototype
Re: CWD in Texas [Re: Frio County Hunts] #5834812 07/16/15 08:51 PM
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A few more positive tests show up, and the entire industry is serious jeopardy. Given CWD's propensity to spread readily in penned herds, I'd find it hard to believe more animals won't test positive.

Re: CWD in Texas [Re: Frio County Hunts] #5834826 07/16/15 08:57 PM
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Sound like they had a compromise in Austin. Tpwd will not slaughter the entire heard. They will kill and test the 29 deer closest to the positive deer. If they get another positive test, they move on to the next closest deer, and so on. A vast majority of breeders can move deer again. The only ranches that cant yet are the ones that bought and sold deer to and from that ranch in Medina.

Apparently the commissioners who made the decision were swayed by a vet who gave testimony about a live test that is 97% accurate. The vet said Texas can lead the nation in CWD research by using science, not slaughtering hundreds of animals.

So it sounds like the breeders won this one. Hopefully Texas does lead the nation in research of this disease. God knows it has the opportunity to do so with all the deer on farms in this state.

Re: CWD in Texas [Re: flounder] #5834868 07/16/15 09:19 PM
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Originally Posted By: flounder

Rare report of deer disease in Texas causes stir

Houston Chronicle

Rare report of deer disease in Texas causes stir, especially since it’s the 8 case of CWD documented in Texas, and the first case of CWD in Captive deer.

here is how I would have titled this article, and why.

Shannon Tompkins Finally Breaks Silence on Texas First Captive CWD Case and Starts Off Spreading False Information About Risk Factors. ...

Thursday, July 16, 2015

http://chronic-wasting-disease.blogspot.com/2015/07/rare-report-of-deer-disease-in-texas.html



This is like the pot calling the kettle black. You posting on your blog that humans are at serious risk is false as well because you have absolutely no facts to back that up.


Marc C. Helfrich
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Re: CWD in Texas [Re: Frio County Hunts] #5834873 07/16/15 09:26 PM
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Blogs are extremely credible sources too. Vlogs are good too.

Re: CWD in Texas [Re: jmh004] #5834877 07/16/15 09:28 PM
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Originally Posted By: jmh004
So are you saying CWD is not rare in Texas? I would think one positive test out of who knows how many deer is pretty rare. These links that you post are always hard to follow. They don't seem to have a sense of direction. Just FYI, not trying to start anything.



there have been 8 confirmed cases of cwd in Texas to date that have been documented. documented is key word...kind regards, terry

Re: CWD in Texas [Re: Pitchfork Predator] #5834883 07/16/15 09:30 PM
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Originally Posted By: Pitchfork Predator
Originally Posted By: flounder

Rare report of deer disease in Texas causes stir

Houston Chronicle

Rare report of deer disease in Texas causes stir, especially since it’s the 8 case of CWD documented in Texas, and the first case of CWD in Captive deer.

here is how I would have titled this article, and why.

Shannon Tompkins Finally Breaks Silence on Texas First Captive CWD Case and Starts Off Spreading False Information About Risk Factors. ...

Thursday, July 16, 2015

http://chronic-wasting-disease.blogspot.com/2015/07/rare-report-of-deer-disease-in-texas.html



This is like the pot calling the kettle black. You posting on your blog that humans are at serious risk is false as well because you have absolutely no facts to back that up.



*** LATE-BREAKING ABSTRACTS PRION 2015 CONFERENCE ***

O18

Zoonotic Potential of CWD Prions

Liuting Qing1, Ignazio Cali1,2, Jue Yuan1, Shenghai Huang3, Diane Kofskey1, Pierluigi Gambetti1, Wenquan Zou1, Qingzhong Kong1 1Case Western Reserve University, Cleveland, Ohio, USA, 2Second University of Naples, Naples, Italy, 3Encore Health Resources, Houston, Texas, USA

Chronic wasting disease (CWD) is a widespread and expanding prion disease in free-ranging and captive cervid species in North America. The zoonotic potential of CWD prions is a serious public health concern. Current literature generated with in vitro methods and in vivo animal models (transgenic mice, macaques and squirrel monkeys) reports conflicting results. The susceptibility of human CNS and peripheral organs to CWD prions remains largely unresolved. In our earlier bioassay experiments using several humanized transgenic mouse lines, we detected protease-resistant PrPSc in the spleen of two out of 140 mice that were intracerebrally inoculated with natural CWD isolates, but PrPSc was not detected in the brain of the same mice. Secondary passages with such PrPSc-positive CWD-inoculated humanized mouse spleen tissues led to efficient prion transmission with clear clinical and pathological signs in both humanized and cervidized transgenic mice. Furthermore, a recent bioassay with natural CWD isolates in a new humanized transgenic mouse line led to clinical prion infection in 2 out of 20 mice. These results indicate that the CWD prion has the potential to infect human CNS and peripheral lymphoid tissues and that there might be asymptomatic human carriers of CWD infection.

==================

***These results indicate that the CWD prion has the potential to infect human CNS and peripheral lymphoid tissues and that there might be asymptomatic human carriers of CWD infection.***

==================

P.105: RT-QuIC models trans-species prion transmission

Kristen Davenport, Davin Henderson, Candace Mathiason, and Edward Hoover Prion Research Center; Colorado State University; Fort Collins, CO USA

The propensity for trans-species prion transmission is related to the structural characteristics of the enciphering and heterologous PrP, but the exact mechanism remains mostly mysterious. Studies of the effects of primary or tertiary prion protein structures on trans-species prion transmission have relied primarily upon animal bioassays, making the influence of prion protein structure vs. host co-factors (e.g. cellular constituents, trafficking, and innate immune interactions) difficult to dissect. As an alternative strategy, we used real-time quakinginduced conversion (RT-QuIC) to investigate trans-species prion conversion.

To assess trans-species conversion in the RT-QuIC system, we compared chronic wasting disease (CWD) and bovine spongiform encephalopathy (BSE) prions, as well as feline CWD (fCWD) and feline spongiform encephalopathy (FSE). Each prion was seeded into each host recombinant PrP (full-length rPrP of white-tailed deer, bovine or feline). We demonstrated that fCWD is a more efficient seed for feline rPrP than for white-tailed deer rPrP, which suggests adaptation to the new host.

Conversely, FSE maintained sufficient BSE characteristics to more efficiently convert bovine rPrP than feline rPrP. Additionally, human rPrP was competent for conversion by CWD and fCWD. ***This insinuates that, at the level of protein:protein interactions, the barrier preventing transmission of CWD to humans is less robust than previously estimated.

================

***This insinuates that, at the level of protein:protein interactions, the barrier preventing transmission of CWD to humans is less robust than previously estimated.***

================

https://prion2015.files.wordpress.com/2015/05/programguide1.pdf

Re: CWD in Texas [Re: Frio County Hunts] #5834885 07/16/15 09:32 PM
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Ok, so 8 confirmed cases against the millions of deer in Texas. Sounds unbelievably rare to me.

Re: CWD in Texas [Re: Pitchfork Predator] #5834888 07/16/15 09:32 PM
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Originally Posted By: Pitchfork Predator
Originally Posted By: flounder

Rare report of deer disease in Texas causes stir

Houston Chronicle

Rare report of deer disease in Texas causes stir, especially since it’s the 8 case of CWD documented in Texas, and the first case of CWD in Captive deer.

here is how I would have titled this article, and why.

Shannon Tompkins Finally Breaks Silence on Texas First Captive CWD Case and Starts Off Spreading False Information About Risk Factors. ...

Thursday, July 16, 2015

http://chronic-wasting-disease.blogspot.com/2015/07/rare-report-of-deer-disease-in-texas.html



This is like the pot calling the kettle black. You posting on your blog that humans are at serious risk is false as well because you have absolutely no facts to back that up.


part 2 ;


HUMANS

In conclusion, an analysis of dietary histories revealed statistical associations between various meats/animal products and INCREASED RISK OF CJD. When some account was taken of possible confounding, the association between VEAL EATING AND RISK OF CJD EMERGED AS THE STRONGEST OF THESE ASSOCIATIONS STATISTICALLY. ...

snip...

In the study in the USA, a range of foodstuffs were associated with an increased risk of CJD, including liver consumption which was associated with an apparent SIX-FOLD INCREASE IN THE RISK OF CJD. By comparing the data from 3 studies in relation to this particular dietary factor, the risk of liver consumption became non-significant with an odds ratio of 1.2 (PERSONAL COMMUNICATION, PROFESSOR A. HOFMAN. ERASMUS UNIVERSITY, ROTTERDAM). (???...TSS)

snip...see full report ;

http://collections.europarchive.org/tna/20090505194948/http://bseinquiry.gov.uk/files/yb/1994/08/00004001.pdf

Thursday, October 10, 2013

*************CJD REPORT 1994 increased risk for consumption of veal and venison and lamb**************

http://creutzfeldt-jakob-disease.blogspot.com/2013/10/cjd-report-1994-increased-risk-for.html

CJD9/10022

October 1994

Mr R.N. Elmhirst Chairman British Deer Farmers Association Holly Lodge Spencers Lane BerksWell Coventry CV7 7BZ

Dear Mr Elmhirst,

CREUTZFELDT-JAKOB DISEASE (CJD) SURVEILLANCE UNIT REPORT

Thank you for your recent letter concerning the publication of the third annual report from the CJD Surveillance Unit. I am sorry that you are dissatisfied with the way in which this report was published.

The Surveillance Unit is a completely independant outside body and the Department of Health is committed to publishing their reports as soon as they become available. In the circumstances it is not the practice to circulate the report for comment since the findings of the report would not be amended. In future we can ensure that the British Deer Farmers Association receives a copy of the report in advance of publication.

The Chief Medical Officer has undertaken to keep the public fully informed of the results of any research in respect of CJD. This report was entirely the work of the unit and was produced completely independantly of the the Department.

The statistical results reqarding the consumption of venison was put into perspective in the body of the report and was not mentioned at all in the press release. Media attention regarding this report was low key but gave a realistic presentation of the statistical findings of the Unit. This approach to publication was successful in that consumption of venison was highlighted only once by the media ie. in the News at one television proqramme.

I believe that a further statement about the report, or indeed statistical links between CJD and consumption of venison, would increase, and quite possibly give damaging credence, to the whole issue. From the low key media reports of which I am aware it seems unlikely that venison consumption will suffer adversely, if at all.

http://web.archive.org/web/20030511010117/http://www.bseinquiry.gov.uk/files/yb/1994/10/00003001.pdf

Thursday, October 10, 2013

*** CJD REPORT 1994 increased risk for consumption of veal and venison and lamb

http://creutzfeldt-jakob-disease.blogspot.com/2013/10/cjd-report-1994-increased-risk-for.html

PLUS, THE CDC DID NOT PUT THIS WARNING OUT FOR THE WELL BEING OF THE DEER AND ELK ;

Thursday, May 26, 2011

Travel History, Hunting, and Venison Consumption Related to Prion Disease Exposure, 2006-2007 FoodNet Population Survey Journal of the American Dietetic Association Volume 111, Issue 6 , Pages 858-863, June 2011. http://transmissiblespongiformencephalop...nd-venison.html

NOR IS THE FDA recalling this CWD positive elk meat for the well being of the dead elk ;

Wednesday, March 18, 2009

Noah's Ark Holding, LLC, Dawson, MN RECALL Elk products contain meat derived from an elk confirmed to have CWD NV, CA, TX, CO, NY, UT, FL, OK RECALLS AND FIELD CORRECTIONS: FOODS CLASS II

http://chronic-wasting-disease.blogspot.com/2009/03/noahs-ark-holding-llc-dawson-mn-recall.html

now, let’s see what the authors said about this casual link, personal communications years ago. see where it is stated NO STRONG evidence. so, does this mean there IS casual evidence ???? “Our conclusion stating that we found no strong evidence of CWD transmission to humans”

From: TSS (216-119-163-189.ipset45.wt.net) Subject: CWD aka MAD DEER/ELK TO HUMANS ???

Date: September 30, 2002 at 7:06 am PST From: "Belay, Ermias"

To: Cc: "Race, Richard (NIH)" ; ; "Belay, Ermias"

Sent: Monday, September 30, 2002 9:22 AM

Subject: RE: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS

Dear Sir/Madam,

In the Archives of Neurology you quoted (the abstract of which was attached to your email), we did not say CWD in humans will present like variant CJD. That assumption would be wrong. I encourage you to read the whole article and call me if you have questions or need more clarification (phone: 404-639-3091). Also, we do not claim that "no-one has ever been infected with prion disease from eating venison." Our conclusion stating that we found no strong evidence of CWD transmission to humans in the article you quoted or in any other forum is limited to the patients we investigated.

Ermias Belay, M.D. Centers for Disease Control and Prevention

-----Original Message-----

From:

Sent: Sunday, September 29, 2002 10:15 AM

To: rr26k@nih.gov; rrace@niaid.nih.gov; ebb8@CDC.GOV

Subject: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS Sunday, November 10, 2002 6:26 PM ......snip........end..............TSS

Thursday, April 03, 2008

A prion disease of cervids: Chronic wasting disease

2008 1: Vet Res. 2008 Apr 3;39(4):41 A prion disease of cervids: Chronic wasting disease Sigurdson CJ.

snip...

*** twenty-seven CJD patients who regularly consumed venison were reported to the Surveillance Center***,

snip... full text ;

http://chronic-wasting-disease.blogspot.com/2008/04/prion-disease-of-cervids-chronic.html

*** These results would seem to suggest that CWD does indeed have zoonotic potential, at least as judged by the compatibility of CWD prions and their human PrPC target. Furthermore, extrapolation from this simple in vitro assay suggests that if zoonotic CWD occurred, it would most likely effect those of the PRNP codon 129-MM genotype and that the PrPres type would be similar to that found in the most common subtype of sCJD (MM1).

https://www.landesbioscience.com/journals/prion/article/28124/?nocache=112223249

*** The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. These circumstances represent a potential threat to blood, blood products, and plasma supplies.

http://cdmrp.army.mil/prevfunded/nprp/NPRP_Summit_Final_Report.pdf


kind regards, terry

Re: CWD in Texas [Re: Frio County Hunts] #5834890 07/16/15 09:33 PM
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You can stop posting the exact same thing over and over again too. We got it!

Re: CWD in Texas [Re: jmh004] #5834892 07/16/15 09:33 PM
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Originally Posted By: jmh004
Ok, so 8 confirmed cases against the millions of deer in Texas. Sounds unbelievably rare to me.


Thank you sir.



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