Tried something today that while I have not heard or found where someone has actually done this I did find precedence.
I saw where someone had taken 22-250 brass and used Cream of Wheat and pistol powder to form to 6.5 Creedmoor
It seemed to me that if that was possible why could I not just shoot 22-250 ammo thru my 22 Creedmoor.
So I took 10 Nosler once fired cases simply neck sized and loaded a starting charge of H4831 using 22-250 Ackley fast twist data .Then seated 85 gr Barnes Matchburners .030 into the lands to hold the case tight against the bolt face and went to the range and shot 5 of them thru the chronograph.
As you can see it seemed to be a mild load which I expected.
Almost shot to the same POI as the normal load going 600fps faster.
Best pic for last...
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"Anyone taking up handloading necessarily plays with unknown factors and takes chances. But so does anyone who drives a car,goes to a cocktail party,eats in a restaurant,or gets married."
Jack O'Connor 1963