In 2004 I started using inline muzzleloaders for all my big game hunting. The majority of my time is spent on my lease near Sonora where I primarily hunt whitetails. We also have axis, fallow, aoudad and feral hogs. I have 3 Knights, all 50 cal. All 3 have bare primer breech plugs and adjustable triggers. After a lot of range time I'v settled on a 100 gr load of BH 209 by volume(I also weigh it for consistency), a Winchester regular 209 primer, Harvester's black crush rib sabot and their 300 gr. PT Gold bullet. Load is extremely accurate as well as deadly.Lots of other good choices out there.
I pick my shots and usually limit them to 150 yds however I am not afraid to reach out further if I have a solid rest. I have learned a lot in the field, however there is a lot of great info on the internet. Take a look at huntingnet.com-Firearms forum- "Blackpowder"; modernmuzzleloading.com "Inline Muzzleloading and namlhunt.com just to name a few. They are a lot of fun to shoot and its a challenge. Enjoy