I remember coyote hunting in western Nebraska a few years ago and the wind was blowing hard. When I put the data into my app, it said i needed adjust so many clicks or 42" to the right to account for wind drift. Many basic hunting scopes don't have that much adjustment in them....It was easy to guess 42" and I dropped the coyote on the first shot. Not sure if it was luck or skill, but I know without the app to tell me the windage amount, I wouldn't have came close.
I have one scope with the wind plex, but have found it useless. Much easier to let the app tell you how many clicks or how far for "kentucky windage"
Luck.
Distance is science, wind is art.
With known holds, in Mils, based on known cross wind, guessing that cross wind, down range, is the art.