Would it matter what they are for? I wouldn't worry about it for uncrimped ammo, but is that enough variation to give you any issues with calibers that head space off of the case mouth like 9mm etc.? or enough variation to mess with crimping/roll crimping? If I'm crimping I always trim cases.
Yes, it would matter. If you roll crimp (like for a bottlenecked round, 308, 223, etc), a varying case length will cause varying amounts of crimp, which will effect your pressures from round to round, and will have inconsistent ammo. If you have a round like the 9mm or 40 cal that head space off the case mouth, I taper crimp these. This will still crimp but allow less variation from round to round with a varying case length. I load tons of mixed head stamp brass for 40 cal for my personal ammo. I don't worry about case length and crimping since I taper crimp them.
I use a Lee crimp die that squeezes the neck for a crimp, which will allow for a varying case neck length and not have a big issue with varying crimp tension. So, I change up what crimp method I use to account for the variations.