Based on the grid what is y’all’s preferred or optimal shot placement? I’ve always had pretty good luck with straight up the leg like E6 or D6, but that tends to waist a little more meat than behind the shoulder.

E7 for me,

C6 or D6. I want to blow out the shoulder so they’re less likely to run through the brush and it leaves room for a miss.

I always go for D to E 7.

E-7 and just give them a few minutes to pile up if they don't drop at the shot.

C7, specifically that one hair I see inside the top of that location.

C6 - 7

Depends on the situation but I like C-6, F-7 and C-4.

You sunk my battle ship!

E-6 or D-6 for me.

Doe, spike, cull = B-1 if the animal is no more than 150 yards and I have a rock steady rest with a solid anchor point for my elbow. If not, then D/E-7

Trophy = D-6 for me to try and anchor him where he stands and also to allow an inch or 2 either way.

But to be perfectly honest I don't really like completely broadsided shots. I'd rather have a big deer quartering towards me and then he gets it in C/D-4 which breaks them down 90%+ of the time.

Broadside, standing still? C4

He needs another year.

Until this year I was always a D7, E7 kind of guy. Had a buck come out this year early evening and decided I didn't want to be tracking by myself in the dark so I shot for C6 and it was DRT. Now a huge fan of C6.

If it's truly a broadside shot at a reasonable distance with a solid rest, C4 / D4. If the distance is further out then D6.

C4 with a rest E7 if not

Anywhere from the top of C to middle of E along the line between 6/5, it all depends on how far the deer is and how he is standing. Most of the time it will be at the four corner intersection of C-D-5-6.

F-7

C4 -broadside
D7

D-14

D7 or E7 for me.

c6

Pending distance, weather, rest, my own steadiness at the time, weapon etc. Just about anything inside the red.

D6 if straight broadside. Alter the position, lots of different options.

Basically where D6 and D7 meet. I think that gives you about 2 squares in EVERY direction in case your shot is off a little.
If I thought I could hit exactly where I wanted then that opens up a lot of options but I NEVER rely of hitting exactly where I want and especially not at longer distance or any other negative variable. I want to allow for the most margin of error in case my shot is a little off. I think up and down that D is in the middle of the kill zone and left to right 7 is probably in the middle. A little unsure of shot making I would hedge into D7 but if confident I would hedge into D6. Getting above D can really break them down on the spot but not enough margin for error.
I am only referring to a shot on a big Trophy buck where the highest percentage of kill is critical.

I’m not real good at drawing on a pic but this shows what I think gives a lot of margin for error.