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Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road #7391349 12/31/18 06:04 PM
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Greetings Texas hunters et al,

i put together a end of year report of sorts for the cwd tse prion that i thought some here might be interested in. others not so much. but to all of you and yours, Happy New Year, i pray 2019 brings us much good news about the cwd tse prion...GOOD LUCK!

FRIDAY, DECEMBER 28, 2018

Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road

https://chronic-wasting-disease.blogspot.com/2018/12/chronic-wasting-disease-cwd-tse-prion.html


kind regards, terry


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Last edited by flounder; 12/31/18 06:05 PM.
Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: flounder] #7391373 12/31/18 06:24 PM
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Originally Posted by bill oxner
I plowed mules.
Originally Posted by Roll-Tide
I did build a cabin. Aka the brokeback shack.

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Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: SapperTitan] #7391412 12/31/18 06:49 PM
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reply to [quote=SapperTitan] ;

***> NORWAY CWD UPDATE December 2018

Report from the Norwegian Scientific Committee for Food and Environment (VKM) 2018: 16

Factors that can contribute to spread of CWD Ė an update on the situation in Nordfjella, Norway

Opinion of Panel on biological hazards of the Norwegian Scientific Committee for Food and Environment

13.12.2018

ISBN: 978-82-8259-316-8

ISSN: 2535-4019

Norwegian Scientific Committee for Food and Environment (VKM)

Po 222 SkÝyen

0213 Oslo

Norway

FRIDAY, DECEMBER 14, 2018

Norway, Nordfjella VKM 2018 16 Factors that can contribute to spread of CWD TSE Prion UPDATE December 14, 2018

https://vkm.no/download/18.696229a7.../CWD%20factors%20for%20spread%202018.pdf

https://chronic-wasting-disease.blogspot.com/2018/12/norway-nordfjella-vkm-2018-16-factors.html

THURSDAY, OCTOBER 25, 2018

***> Norway New additional requirements for imports of hay and straw for animal feed from countries outside the EEA due to CWD TSE Prion

https://www.mattilsynet.no/dyr_og_d...r_EoeSomraadet&utm_content=Dyrehelse

https://chronic-wasting-disease.blogspot.com/2018/10/norway-new-additional-requirements-for.html

***> cwd scrapie pigs oral routes

***> However, at 51 months of incubation or greater, 5 animals were positive by one or more diagnostic methods. Furthermore, positive bioassay results were obtained from all inoculated groups (oral and intracranial; market weight and end of study) suggesting that swine are potential hosts for the agent of scrapie. <***

>*** Although the current U.S. feed ban is based on keeping tissues from TSE infected cattle from contaminating animal feed, swine rations in the U.S. could contain animal derived components including materials from scrapie infected sheep and goats. These results indicating the susceptibility of pigs to sheep scrapie, coupled with the limitations of the current feed ban, indicates that a revision of the feed ban may be necessary to protect swine production and potentially human health. <***

***> Results: PrPSc was not detected by EIA and IHC in any RPLNs. All tonsils and MLNs were negative by IHC, though the MLN from one pig in the oral <6 month group was positive by EIA. PrPSc was detected by QuIC in at least one of the lymphoid tissues examined in 5/6 pigs in the intracranial <6 months group, 6/7 intracranial >6 months group, 5/6 pigs in the oral <6 months group, and 4/6 oral >6 months group. Overall, the MLN was positive in 14/19 (74%) of samples examined, the RPLN in 8/18 (44%), and the tonsil in 10/25 (40%).

***> Conclusions: This study demonstrates that PrPSc accumulates in lymphoid tissues from pigs challenged intracranially or orally with the CWD agent, and can be detected as early as 4 months after challenge. CWD-infected pigs rarely develop clinical disease and if they do, they do so after a long incubation period.

***> This raises the possibility that CWD-infected pigs could shed prions into their environment long before they develop clinical disease.

***> Furthermore, lymphoid tissues from CWD-infected pigs could present a potential source of CWD infectivity in the animal and human food chains.

>>>> The successful transmission of pig-passaged CWD to Tg40 mice reported here suggests that passage of the CWD agent through pigs results in a change of the transmission characteristics which reduces the transmission barrier of Tg40 mice to the CWD agent. If this biological behavior is recapitulated in the original host species, passage of the CWD agent through pigs could potentially lead to increased pathogenicity of the CWD agent in humans.

https://www.ars.usda.gov/research/publications/publication/?seqNo115=353091

https://www.ars.usda.gov/research/project/?accnNo=432011&fy=2017

https://www.ars.usda.gov/research/publications/publication/?seqNo115=337105

Friday, December 14, 2012

DEFRA U.K. What is the risk of Chronic Wasting Disease CWD being introduced into Great Britain? A Qualitative Risk Assessment October 2012

snip.....

In the USA, under the Food and Drug Administration's BSE Feed Regulation (21 CFR 589.2000) most material (exceptions include milk, tallow, and gelatin) from deer and elk is prohibited for use in feed for ruminant animals. With regards to feed for non-ruminant animals, under FDA law, CWD positive deer may not be used for any animal feed or feed ingredients. For elk and deer considered at high risk for CWD, the FDA recommends that these animals do not enter the animal feed system. However, this recommendation is guidance and not a requirement by law.

Animals considered at high risk for CWD include:

1) animals from areas declared to be endemic for CWD and/or to be CWD eradication zones and

2) deer and elk that at some time during the 60-month period prior to slaughter were in a captive herd that contained a CWD-positive animal.

Therefore, in the USA, materials from cervids other than CWD positive animals may be used in animal feed and feed ingredients for non-ruminants.

The amount of animal PAP that is of deer and/or elk origin imported from the USA to GB can not be determined, however, as it is not specified in TRACES. It may constitute a small percentage of the 8412 kilos of non-fish origin processed animal proteins that were imported from US into GB in 2011.

Overall, therefore, it is considered there is a __greater than negligible risk___ that (nonruminant) animal feed and pet food containing deer and/or elk protein is imported into GB.

There is uncertainty associated with this estimate given the lack of data on the amount of deer and/or elk protein possibly being imported in these products.

snip.....

36% in 2007 (Almberg et al., 2011). In such areas, population declines of deer of up to 30 to 50% have been observed (Almberg et al., 2011). In areas of Colorado, the prevalence can be as high as 30% (EFSA, 2011).

The clinical signs of CWD in affected adults are weight loss and behavioural changes that can span weeks or months (Williams, 2005). In addition, signs might include excessive salivation, behavioural alterations including a fixed stare and changes in interaction with other animals in the herd, and an altered stance (Williams, 2005). These signs are indistinguishable from cervids experimentally infected with bovine spongiform encephalopathy (BSE).

Given this, if CWD was to be introduced into countries with BSE such as GB, for example, infected deer populations would need to be tested to differentiate if they were infected with CWD or BSE to minimise the risk of BSE entering the human food-chain via affected venison.

snip.....

The rate of transmission of CWD has been reported to be as high as 30% and can approach 100% among captive animals in endemic areas (Safar et al., 2008).

snip.....

In summary, in endemic areas, there is a medium probability that the soil and surrounding environment is contaminated with CWD prions and in a bioavailable form. In rural areas where CWD has not been reported and deer are present, there is a greater than negligible risk the soil is contaminated with CWD prion.

snip.....

In summary, given the volume of tourists, hunters and servicemen moving between GB and North America, the probability of at least one person travelling to/from a CWD affected area and, in doing so, contaminating their clothing, footwear and/or equipment prior to arriving in GB is greater than negligible... For deer hunters, specifically, the risk is likely to be greater given the increased contact with deer and their environment. However, there is significant uncertainty associated with these estimates.

snip.....

Therefore, it is considered that farmed and park deer may have a higher probability of exposure to CWD transferred to the environment than wild deer given the restricted habitat range and higher frequency of contact with tourists and returning GB residents.

snip.....

http://webarchive.nationalarchives.gov.uk/20130908115835/http://www.defra.gov.uk/animal-diseases/files/qra_chronic-wasting-disease-121029.pdf

2019 prepare for the storm...tss

When making policy legislative decisions, regulations, and law, for a disease such as cwd tse prion in cervid, it is crucial that you have all the science, and you must understand the science. this is a difficult thing to do for hunters when you have the industry and corporate lobbyist there from, feeding your politicians junk science in one hand, and a fist full of dollars in another. you die hard idiots that follow ted nugent for your science deserve what you get. you keep following bs like that, you will lose your cervid herd as you know in the long run. your children will not know it as you do. so what is it, uncle ted theology which is horse [censored], or sound science. listen to the scientist.

WITH the recent findings that Scrapie will transmit to Macaque by oral route, that Scrapie and CWD TSE Prion will transit to pigs orally, recent outbreak documented of TSE Prion Disease in Dromedary Camels, Algeria, atypical TSE Prion still being documented, and again just recently in the USA, of another atypical BSE case, and this discovery was only documented by testing 20k head of cattle from some 100M head of cattle in any given year in the USA, the continued denial that atypical BSE and atypical Scrapie are a transmissible disease (science has shown otherwise) this is concerning to me.

Science and scientific policy makers have forgotten what Gibbs, Gajdusek, Hadlow, Alper, Zigas, even Gordon with the infamous Scrapie vaccine blunder, a discovery of valuable importance, and so many others i am failing to remember now, what some found long ago, like Dr. Gibbs, he tried to warn us about scrapie zoonosis potential, yet that went ignored for decades and decades.

we/scientist/officials/the world, knows the USA FDA PART 589 TSE PRION FEED ban has failed terribly, the BSE testing has failed terribly, and the surveillance there from has failed, SRM removal breaches, all proven by the OIG or the GAO, and others.

But yet, we find ourselves now debating the issue of these same risk factors for scrapie, the same risk factors that we all knew were there, with science staring us in the face, we still deny scientific facts all in the name of corporate interest.

let's not continue to make these same mistakes. human and animal life is at stake here. we must remove corporate/government/lobbyist interest from the scientific policy making and regulations there from for the TSE Prion, all of them.

I urge you all to take a good look at the most recent science i have put together here for you. this is a free full course of the tse prion disease.

cwd tse prion

cwd and scrapie has now been documented to transmit to pigs BY ORAL ROUTE, this is terrible news. FEED, FEED, FEED!

I KINDLY WISH TO SUBMIT THE FOLLOWING LATEST SCIENCE ON THE CHRONIC WASTING DISEASE CWD TSE PRION.

THE TSE PRION aka mad cow type disease is not your normal pathogen.

The TSE prion disease survives ashing to 600 degrees celsius, thatís around 1112 degrees farenheit.

you cannot cook the TSE prion disease out of meat.

you can take the ash and mix it with saline and inject that ash into a mouse, and the mouse will go down with TSE.

Prion Infected Meat-and-Bone Meal Is Still Infectious after Biodiesel Production as well.

the TSE prion agent also survives Simulated Wastewater Treatment Processes.

IN fact, you should also know that the TSE Prion agent will survive in the environment for years, if not decades.

you can bury it and it will not go away.

The TSE agent is capable of infected your water table i.e. Detection of protease-resistant cervid prion protein in water from a CWD-endemic area.

itís not your ordinary pathogen you can just cook it out and be done with.

***> thatís whatís so worrisome about Iatrogenic mode of transmission, a simple autoclave will not kill this TSE prion agent.

this old study next always stuns me. think of this the next time you clean your tools you use to gut and bone out your kill, and then feeding it to your family and friends...tss

1: J Neurol Neurosurg Psychiatry 1994 Jun;57(6):757-8

***> Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery.

Gibbs CJ Jr, Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC.

Laboratory of Central Nervous System Studies, National Institute of

Neurological Disorders and Stroke, National Institutes of Health,

Bethesda, MD 20892.

Stereotactic multicontact electrodes used to probe the cerebral cortex of a middle aged woman with progressive dementia were previously implicated in the accidental transmission of Creutzfeldt-Jakob disease (CJD) to two younger patients. The diagnoses of CJD have been confirmed for all three cases. More than two years after their last use in humans, after three cleanings and repeated sterilisation in ethanol and formaldehyde vapour, the electrodes were implanted in the cortex of a chimpanzee. Eighteen months later the animal became ill with CJD. This finding serves to re-emphasise the potential danger posed by reuse of instruments contaminated with the agents of spongiform encephalopathies, even after scrupulous attempts to clean them.

PMID: 8006664 [PubMed - indexed for MEDLINE]

https://www.ncbi.nlm.nih.gov/pubmed/8006664?dopt=Abstract

At this stage, the characterization of the strain diversity and zoonotic abilities associated with animal prion diseases remain largely incomplete. However, transmission experiments in non&#8208;human primates and transgenic mice expressing human PrP clearly indicate that classical scrapie, and certain forms of atypical BSE (L&#8208;BSE) or CWD may have the potential to infect humans. The remaining uncertainties about the origins and relationships between animal prion diseases emphasizes the importance of the measures implemented to limit human exposure to these potentially zoonotic agents, and of continued surveillance for both animal and human prion diseases.

This article is protected by copyright. All rights reserved.

https://onlinelibrary.wiley.com/doi/abs/10.1111/bpa.12696

Prion diseases continue to fascinate scientists from different disciplines since the discovery that a misfolded prion protein can act as an infectious agent. Infectious prions have caused epidemics, including kuru in humans, cervid chronic wasting disease, bovine spongiform encephalopathy (BSE) or ďmad cow diseaseĒ, and most recently, camel prion disease, which was identified in 2018 (1). In Kuru, spread of the disease occurred from the ingestion of prion&#8208;infected, dead relatives as part of mourning practices, whereas in chronic wasting disease, prions may be transmitted not only through ingesting prion&#8208;contaminated food, but also by exposure to a prion&#8208;contaminated environment(8, 9). In all instances, prions hold structural properties that cause different disease presentations, which can be passed on to another individual (16).

This article is protected by copyright. All rights reserved.

https://onlinelibrary.wiley.com/doi/abs/10.1111/bpa.12693

***> The notion that CWD can be transmitted orally into both new-world and old-world non-human primates asks for a careful reevaluation of the zoonotic risk of CWD. <***

https://prion2018.org/

READING OVER THE PRION 2018 ABSTRACT BOOK, LOOKS LIKE THEY FOUND THAT from this study ;

P190 Human prion disease mortality rates by occurrence of chronic wasting disease in freeranging cervids, United States

Abrams JY (1), Maddox RA (1), Schonberger LB (1), Person MK (1), Appleby BS (2), Belay ED (1) (1) Centers for Disease Control and Prevention (CDC), National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA, USA (2) Case Western Reserve University, National Prion Disease Pathology Surveillance Center (NPDPSC), Cleveland, OH, USA..

SEEMS THAT THEY FOUND Highly endemic states had a higher rate of prion disease mortality compared to non-CWD states.

AND ANOTHER STUDY;

P172 Peripheral Neuropathy in Patients with Prion Disease

Wang H(1), Cohen M(1), Appleby BS(1,2) (1) University Hospitals Cleveland Medical Center, Cleveland, Ohio (2) National Prion Disease Pathology Surveillance Center, Cleveland, Ohio..

IN THIS STUDY, THERE WERE autopsy-proven prion cases from the National Prion Disease Pathology Surveillance Center that were diagnosed between September 2016 to March 2017,

AND

included 104 patients. SEEMS THEY FOUND THAT The most common sCJD subtype was MV1-2 (30%), followed by MM1-2 (20%),

AND

THAT The Majority of cases were male (60%), AND half of them had exposure to wild game.

snip...see more on Prion 2017 Macaque study from Prion 2017 Conference and other updated science on cwd tse prion zoonosis below...terry

https://prion2018.org/wp-content/uploads/2018/05/program.pdf

https://prion2018.org/

THURSDAY, OCTOBER 04, 2018

Cervid to human prion transmission 5R01NS088604-04 Update

http://chronic-wasting-disease.blogspot.com/2018/10/cervid-to-human-prion-transmission.html

WEDNESDAY, DECEMBER 12, 2018

Texas TPWD TAHC Chronic Wasting Disease CWD TSE Prion 133 Cases To Date

2018 11/30/2018 Breeder Release Site Medina Facility

https://chronic-wasting-disease.blogspot.com/2018/12/texas-tpwd-tahc-chronic-wasting-disease.html

carry on!

terry

Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: flounder] #7391435 12/31/18 07:06 PM
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This could be bigger than Y2K

Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: flounder] #7391436 12/31/18 07:07 PM
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Here we go again..... spam troll


Originally Posted By: skinnerback
Milf does the trick.

"You're statistically more likely to be killed by Hillary Clinton than an NRA member. - PolitiDiva

"You Cannot Simultaneously Be Politically Correct And Intellectually Honest!"
Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: maximus_flavius] #7391979 01/01/19 03:35 AM
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Originally Posted by maximus_flavius
This could be bigger than Y2K


Check out my new shirt, Iím bringing sexy back

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Donate to TX Youth hunting program.... better to donate then to waste it in taxes

https://secure.qgiv.com/for/gtgoh/mobile
Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: flounder] #7391998 01/01/19 04:00 AM
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No this chit again... bang There is not one person on here interested in your "research"


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Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: BOBO the Clown] #7392073 01/01/19 06:17 AM
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Originally Posted by BOBO the Clown
Originally Posted by maximus_flavius
This could be bigger than Y2K


Check out my new shirt, Iím bringing sexy back

[Linked Image]





Sweet!!! Do they make that in a tank top, midriff in size 4XXXXL? Iím workin on some killer abs that Iíd like to show off.

Re: Chronic Wasting Disease CWD TSE Prion 2019 Where The Rubber Meets The Road [Re: 2Beez] #7392075 01/01/19 06:19 AM
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Originally Posted by 2Beez
No this chit again... bang There is not one person on here interested in your "research"



You misspelled ďcopy pastaĒ.

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