My .243 has killed everything it has hit.

Not saying everything it was shot at

But everything it has connected with.

I'll stick with my Weatherby's, with that said I've killed a ton of critters with a 243. On deer size game Mrs. B probably has more experience with a 243 than I do so I'll share that. Her first year with the 243 she dropped two bucks in their tracks with neck shots, one doe with a shoulder shot and it went about 60 tards. Second year I buck with a shoulder shot and it went over 150 yards, one doe with a neck shot and again in it's tracks. Year 3 we went after elk so moved her up to a 7mm08, one shot in the heart lung on a 3 year old bull and he went less than 50 yards, two shoulder shots on bucks and they both dropped in their tracks. She is now a fan of the 7mm08 as am I, when it comes to a medium sized all around caliber the little 7mm is hard to beat. I left out the hogs she shot because those were all head shoots. Our 243's have been pushed back to varmint level and with probably remain there, I'll never use another one on deer and Mrs. B is sold on the 7mm08.

Actually, Hooper, the 7mm08 is a couple bumps up from the .243. Bigger lead, more powder, harder stats but yet easy on the shoulder. Both are sweet calibers.

What's the advantage of the 7-08 over the 243?

Yep .243 will do it but I'll stick with my .257 Roy