Hodgdon Clays powders have 3 different powders in the family.
Clays is the fastest burning of the 3 and I have loaded pounds upon pounds of it for 12ga target and dove loads. Also it is listed for light handgun loads in many cases. This powder I switched to for competition 12ga shotgun loads when it came out. Shoot 3 rounds of trap or skeet and the barrel has less powder residue than 5 shots of shells loaded with Red Dot powder. I have shot lots of lead plinking loads in the 38 special using this powder but caution to never double charge as its loads would fir for sure.
Clays International is the medium burning of the family and I have not seen handgun data for it in years. Mostly I have used this one for 12ga light skeet and hunting loads.
Clays Universal like the name indicates it is very adaptive and useful in some smaller guage guns like 20 and 28 but is also used in lots of handgun loads. If I recall correctly this powder is close to Unique in burn rate and versatility
All three are clean burning powders.
Go to this page for lots of handgun and shotgun data using these powders as well as Winchester and IMR powders
http://www.hodgdonreloading.com/