Help decide on a varmint rifle

I'm looking to buy a new rifle for coyotes prairie dogs and possible bobcats. I was thinking either a .204, .243, .223, or .22-250. I'll be hunting in central and west texas. Any input on these calibers or any others would be appreciated. Thanks

22-250

22-250. I've got one and wouldn't get rid of it.

223/22-250/220 swift for dedicated varmint gun. For mulitpurpose a 243 could do it with a light bullet and you could use a heavier bullet to deer hunt.

I'm a 6mm slut but I still have a 223 and 220 swift.

That 22-250 gets it done and decent ammo selections here is a different caliber to look at 223 wssm

If you're intent on hot and heavy prairie dog shooting you'd be best off with something in .223 Rem unless you can restrain yourself from toasting the barrel on a .22-250.

.223

all of those you listed are great. chose the one best for you

I've fallen for the 204 myself in a CZ varmint target 527 with the Kevlar stock. Dang I love that thing! And it's truly a great value!

22-250, my rifle, 80gr amaxs at 3200fps

or the exotic 22-Creedmoor

But as always, the 22-250 will win I'm sure.

22 creedmoor 75 grainer in a 22 inch barrel I am going 3320

CZ 527 in .223

.22-250 hands down and don't worry about barrel life.....

.223

.204 all day every day

Easier on the barrel super easy on the shoulder, bucks the wind and hits HARD. I really want a can for my cousins... but if he got one I might end up borrowing it indefinitely.

just read this, this is the exact gun my cousin has LOVE that thing.

under 400, but with the heavier higher BC bullets the creed has way less wind drift and drop at 400 out

I'd go 22-250 first then 204, love them both

22-250... shooting Hornady Superformance 50gr at 4025fps. It zings and is darn flat. It only drops 4.5 inches at 300yds

Thanks for all the input guys! I was thinking of getting a ruger American predator in one these calibera anyone have experience with this gun?