Yes. Here's a doe I shot at ~280 yards with 208 A-max from a few years ago after they first came out. I've had customers take all kinds of critters (elk, bear, caribou) with the 208 A-max. It is a very good bullet for hunting. It provides deep penetration with good expansion.
No. Federal brass is too soft, and will wear out in about 1-3 reloads. Spend the extra money and get some Nosler or Norma brass. It's expensive, but worth it.