I don't think I could hit a garbage can at 100 yds. off hand......LOL
You never know till you try. I shot a huge gobbler out of the air with a browning buckmark .22 pistol. I have two witnesses. And I videoed myself shooting a running javelina in the head with a 357 pistol. Was it luck? He77 yes. But it I wouldn't have had that awesome experience without trying.
I offhand shot the biggest mule deer I've ever seen (admittedly at 75 yards broadside). Would I have rather had a rest? Yes. But I had hunted 5 hard days, it was my last evening, and those deer can disappear extremely quick, and if they're running, it's an up and down nightmare.
I have no problem taking chances with turkey's and varmints. I don't recommend it for big game. But sometimes you gotta go with what's available.