22WMR limits your choice. S&W is costly and only a couple of models have 2" barrels.
Ruger LCR has a stout trigger. Many women do not have the index finger strength. Plus the DA makes it difficult to be accurate with trigger issue.
Might get a Taurus or Charter Arms, both have/had models with 2" barrels.
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it is the illusion of knowledge.--Stephen Hawking