The manuals are general guidelines. Each barrel and combination of brass, bullet, powder, and primer will interact differently. Even different lots of powder will change load data and a max load.
OP, if you want to gain a deeper understanding of things, pick a powder, pick a loading data source, and start with a light bullet. Note Max charge, then go to a heavier bullet, note Max charge, carry on until you run out of published data for the heaviest of bullets listed. You'll see a decrease in Max charge as you increase in bullet weight. That will give you a guideline as to what is a safe Max and what is way too light or way too heavy
Switch to another loading data source and go again.