I have the regular 280 but really not enough difference that powder choices are dissimilar.
I have had good success with H4831/Reloder 26/4000MR/N160 and have some Reloder 23 loads ready to try.
I am running the 168gr Berger Classic Hunter but will be trying the 175gr Hornady ELD-X next.
The Bergers have not failed me though.
"Anyone taking up handloading necessarily plays with unknown factors and takes chances. But so does anyone who drives a car,goes to a cocktail party,eats in a restaurant,or gets married."
Jack O'Connor 1963