They're going to be really close, and I've heard of a lot of folks using the data interchangeably. I certainly wouldn't recommend that without first working up the load as you would with any new powder. Lot to lot variation itself is a good enough reason to start low, and work up. You might find universal to meter a little better, and be a little cleaner burning as well. I searched high and low for Unique for my .45 Colt, and ended up going to Universal because that's what was available at the time.