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Max Online: 16728 @ 03/25/12 08:51 AM
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#6170709 - 02/05/16 11:33 AM Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild
flounder Offline
Woodsman

Registered: 10/29/11
Posts: 174
Loc: 77518
Friday, February 05, 2016

Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild

http://chronic-wasting-disease.blogspot.com/2016/02/report-of-committee-on-wildlife.html


kind regards, terry

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#6170752 - 02/05/16 12:01 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
Pitchfork Predator Online   content
THF Celebrity

Registered: 01/25/13
Posts: 10819
Loc: Murphy, TX Dickens county
If you were in charge Terry, what would you do with that Mule deer herd in west Texas that has a 10% infection rate according to your numbers?
_________________________
Marc C. Helfrich
Retirement Planner

www.insured-wealth.com
469-323-8920

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#6170788 - 02/05/16 12:19 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
flounder Offline
Woodsman

Registered: 10/29/11
Posts: 174
Loc: 77518
we must test in higher numbers across the board, and until a validated cwd test for cervid is approved that is 100% accurate, you are going to have to use the scorched earth policy to do that, like it or not. it's the only way to date. it ain't pretty. but do we all want to leave a legacy of drooling stumbling sick cervid with cwd mad deer disease tse prion for our children ? I don't think so. ...


this just out ;


Friday, February 05, 2016

TEXAS NEW CHRONIC WASTING DISEASE CWD CASE DISCOVERD AT CAPTIVE DEER RELEASE SITE

http://chronic-wasting-disease.blogspot.com/2016/02/texas-new-chronic-wasting-disease-cwd.html



Friday, February 05, 2016

Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild

http://chronic-wasting-disease.blogspot.com/2016/02/report-of-committee-on-wildlife.html


kind regards, terry

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#6170874 - 02/05/16 01:43 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
BenBob Online   content
THF Trophy Hunter

Registered: 01/27/06
Posts: 5824
Loc: Undercover
WHat is the percentage of farmed deer with it versus the percentage of unfarmed deer? Any deer that is exposed to a farmed deer would be considered a farmed deer. On the flip side, I would not consider any mule deer to be a farmed deer, unless there are some ranches that are farming mule deer the way that whitetails that are being farmed.
_________________________
Tired, Wired, and Uninspired

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#6171083 - 02/05/16 04:08 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
stxranchman Offline
Obie Juan Kenobi

Registered: 08/04/10
Posts: 52092
flounder, how many deer for CWD testing did you submit this season?
_________________________


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#6171088 - 02/05/16 04:11 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: stxranchman]
kdkane1971 Offline
Pro Tracker

Registered: 01/30/14
Posts: 1802
Loc: Mesopotamia
Originally Posted By: stxranchman
flounder, how many deer for CWD testing did you submit this season?



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#6171095 - 02/05/16 04:17 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
rifleman Online   crying
Sparkly Pants

Registered: 11/19/08
Posts: 43783
Loc: Kingwood
I sent 0 in for testing. Did my part to lay off the trigger to help stabilize the diseased herd. grin

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#6171307 - 02/05/16 06:41 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: kdkane1971]
BOBO the Clown Offline
decoy

Registered: 04/19/07
Posts: 41089
Loc: Metroplex
Originally Posted By: kdkane1971
Originally Posted By: stxranchman
flounder, how many deer for CWD testing did you submit this season?





X3

Flounder our resident anti hunter

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#6171320 - 02/05/16 06:48 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
BOBO the Clown Offline
decoy

Registered: 04/19/07
Posts: 41089
Loc: Metroplex
Only a mad man would do a mass extermination....then what restock?... Wait it's a dead carcass test.... Can't restock with dead deer...

Guess its better to mass exterminate and stop all this cruel hunting


50 years since CWD was first OBSERVED and we still have elk and Mule deer at ground zero.



Originally Posted By: flounder
we must test in higher numbers across the board, and until a validated cwd test for cervid is approved that is 100% accurate, you are going to have to use the scorched earth policy to do that, like it or not. it's the only way to date. it ain't pretty. but do we all want to leave a legacy of drooling stumbling sick cervid with cwd mad deer disease tse prion for our children ? I don't think so. ...


this just out ;


Friday, February 05, 2016

TEXAS NEW CHRONIC WASTING DISEASE CWD CASE DISCOVERD AT CAPTIVE DEER RELEASE SITE

http://chronic-wasting-disease.blogspot.com/2016/02/texas-new-chronic-wasting-disease-cwd.html



Friday, February 05, 2016

Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild

http://chronic-wasting-disease.blogspot.com/2016/02/report-of-committee-on-wildlife.html


kind regards, terry

Top
#6171324 - 02/05/16 06:50 PM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
fowlplayr Offline
Shenanigans Scorecard keeper

Registered: 08/03/05
Posts: 4261
Loc: Athens/Prosper, TX

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#6172632 - 02/07/16 06:11 AM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
Pitchfork Predator Online   content
THF Celebrity

Registered: 01/25/13
Posts: 10819
Loc: Murphy, TX Dickens county
Originally Posted By: flounder
we must test in higher numbers across the board, and until a validated cwd test for cervid is approved that is 100% accurate, you are going to have to use the scorched earth policy to do that, like it or not. it's the only way to date. it ain't pretty. but do we all want to leave a legacy of drooling stumbling sick cervid with cwd mad deer disease tse prion for our children ? I don't think so. ...


this just out ;


Friday, February 05, 2016

TEXAS NEW CHRONIC WASTING DISEASE CWD CASE DISCOVERD AT CAPTIVE DEER RELEASE SITE

http://chronic-wasting-disease.blogspot.com/2016/02/texas-new-chronic-wasting-disease-cwd.html



Friday, February 05, 2016

Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild

http://chronic-wasting-disease.blogspot.com/2016/02/report-of-committee-on-wildlife.html


kind regards, terry


So is this the way you would treat people if you were their doctor and they had Alzheimers disease?
_________________________
Marc C. Helfrich
Retirement Planner

www.insured-wealth.com
469-323-8920

Top
#6172760 - 02/07/16 08:52 AM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: Pitchfork Predator]
flounder Offline
Woodsman

Registered: 10/29/11
Posts: 174
Loc: 77518
most folks with Alzheimer’s are just put in a home to die, kinda like shooting pens, without the shooting...

I would kindly like to comment further on ;

Alzheimer-type brain pathology may be transmitted by grafts of dura mater

26/01/2016 By Karl Frontzek, et al.:

http://blog.smw.ch/alzheimer-type-brain-...-mater/#respond

Original article | Published 26 January 2016, doi:10.4414/smw.2016.14287

Cite this as: Swiss Med Wkly. 2016;146:w14287

Amyloid-β pathology and cerebral amyloid angiopathy are frequent in iatrogenic Creutzfeldt-Jakob disease after dural grafting

http://www.smw.ch/content/smw-2016-14287/

MY comment as follows ;

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

07 02:27 AM

Terry S. Singeltary Sr. said:

re-Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

2015-12-07 02:27 AM

Terry S. Singeltary Sr. said: re-Evidence for human transmission of amyloid-? pathology and cerebral amyloid angiopathy Nature 525, 247?250 (10 September 2015) doi:10.1038/nature15369 Received 26 April 2015 Accepted 14 August 2015 Published online 09 September 2015 Updated online 11 September 2015 Erratum (October, 2015)

http://www.nature.com/nature/journal/v525/n7568/full/nature15369.html

I would kindly like to comment on the Nature Paper, the Lancet reply, and the newspaper articles.

First, I applaud Nature, the Scientist and Authors of the Nature paper, for bringing this important finding to the attention of the public domain, and the media for printing said findings.

Secondly, it seems once again, politics is getting in the way possibly of more important Transmissible Spongiform Encephalopathy TSE Prion scientific findings. findings that could have great implications for human health, and great implications for the medical surgical arena. but apparently, the government peer review process, of the peer review science, tries to intervene again to water down said disturbing findings.

where have we all heard this before? it’s been well documented via the BSE Inquiry. have they not learned a lesson from the last time?

we have seen this time and time again in England (and other Country’s) with the BSE mad cow TSE Prion debacle.

That ‘anonymous' Lancet editorial was disgraceful. The editor, Dick Horton is not a scientist.

The pituitary cadavers were very likely elderly and among them some were on their way to CJD or Alzheimer's. Not a bit unusual. Then the recipients ? who got pooled extracts injected from thousands of cadavers ? were 100% certain to have been injected with both seeds. No surprise that they got both diseases going after thirty year incubations.

That the UK has a "system in place to assist science journalists" to squash embargoed science reports they find ? alarming? is pathetic.

Sounds like the journalists had it right in the first place: ‘Alzheimer,s may be a transmissible infection? in The Independent to ? You can catch Alzheimer’s? in The Daily Mirror or ? Alzheimer’s bombshell" in The Daily Express

if not for the journalist, the layperson would not know about these important findings.

where would we be today with sound science, from where we were 30 years ago, if not for the cloak of secrecy and save the industry at all cost mentality?

when you have a peer review system for science, from which a government constantly circumvents, then you have a problem with science, and humans die.

to date, as far as documented body bag count, with all TSE prion named to date, that count is still relatively low (one was too many in my case, Mom hvCJD), however that changes drastically once the TSE Prion link is made with Alzheimer?s, the price of poker goes up drastically.

so, who makes that final decision, and how many more decades do we have to wait?

the iatrogenic mode of transmission of TSE prion, the many routes there from, load factor, threshold from said load factor to sub-clinical disease, to clinical disease, to death, much time is there to spread a TSE Prion to anywhere, but whom, by whom, and when, do we make that final decision to do something about it globally? how many documented body bags does it take? how many more decades do we wait? how many names can we make up for one disease, TSE prion?

Professor Collinge et al, and others, have had troubles in the past with the Government meddling in scientific findings, that might in some way involve industry, never mind human and or animal health.

FOR any government to continue to circumvent science for monetary gain, fear factor, or any reason, shame, shame on you.

in my opinion, it?s one of the reasons we are at where we are at to date, with regards to the TSE Prion disease science i.e. money, industry, politics, then comes science, in that order.

greed, corporate, lobbyist there from, and government, must be removed from the peer review process of sound science, it?s bad enough having them in the pharmaceutical aspect of healthcare policy making, in my opinion.

my mother died from confirmed hvCJD, and her brother (my uncle) Alzheimer?s of some type (no autopsy?). just made a promise, never forget, and never let them forget, before I do.

I kindly wish to remind the public of the past, and a possible future we all hopes never happens again. ...

[9. Whilst this matter is not at the moment directly concerned with the iatrogenic CJD cases from hgH, there remains a possibility of litigation here, and this presents an added complication. There are also results to be made available shortly (1) concerning a farmer with CJD who had BSE animals, (2) on the possible transmissibility of Alzheimer?s and (3) a CMO letter on prevention of iatrogenic CJD transmission in neurosurgery, all of which will serve to increase media interest.]

http://web.archive.org/web/20030714222309/www.bseinquiry.gov.uk/files/yb/1992/12/16005001.pdf

http://collections.europarchive.org/tna/20080102232842/http://www.bseinquiry.gov.uk/files/yb/1992/11/04001001.pdf

http://www.plosone.org/annotation/listThread.action?root=82860

Terry S. Singeltary Sr. Bacliff, Texas USA 77518

snip...

***see Singeltary comment ;

http://www.nature.com/nature/journal/v525/n7568/full/nature15369.html#/comments

Subject: 1992 IN CONFIDENCE TRANSMISSION OF ALZHEIMER TYPE PLAQUES TO PRIMATES POSSIBILITY ON A TRANSMISSIBLE PRION REMAINS OPEN

BSE101/1 0136

IN CONFIDENCE

CMO

From: . Dr J S Metiers DCMO

4 November 1992

TRANSMISSION OF ALZHEIMER TYPE PLAQUES TO PRIMATES

1. Thank you for showing me Diana Dunstan's letter. I am glad that MRC have recognised the public sensitivity of these findings and intend to report them in their proper context. 'This hopefully will avoid misunderstanding and possible distortion by the media to portray the results as having more greater significance than the findings so far justify.

2. Using a highly unusual route of transmission (intra-cerebral injection) the researchers have demonstrated the transmission of a pathological process from two cases one of severe Alzheimer's disease the other of Gerstmann-Straussler disease to marmosets. However they have not demonstrated the transmission of either clinical condition as the "animals were behaving normally when killed". As the report emphasises the unanswered question is whether the disease condition would have revealed itself if the marmosets had lived longer. They are planning further research to see if the conditions, as opposed to the partial pathological process, is transmissible.

what are the implications for public health?

3. The route 'of transmission is very specific and in the natural state of things highly unusual. However it could be argued that the results reveal a potential risk, in that brain tissue from these two patients has been shown to transmit a pathological process. Should therefore brain tissue from such cases be regarded as potentially infective? Pathologists, morticians, neuro surgeons and those assisting at neuro surgical procedures and others coming into contact with "raw" human brain tissue could in theory be at risk. However, on a priori grounds given the highly specific route of transmission in these experiments that risk must be negligible if the usual precautions for handling brain tissue are observed.

1

92/11.4/1.1

BSE101/1 0137

4. The other dimension to consider is the public reaction. To some extent the GSS case demonstrates little more than the transmission of BSE to a pig by intra-cerebral injection. If other prion diseases can be transmitted in this way it is little surprise that some pathological findings observed in GSS were also transmissible to a marmoset. But the transmission of features of Alzheimer's pathology is a different matter, given the much greater frequency of this disease and raises the unanswered question whether some cases are the result of a transmissible prion. The only tenable public line will be that "more research is required’’ before that hypothesis could be evaluated. The possibility on a transmissible prion remains open. In the meantime MRC needs carefully to consider the range and sequence of studies needed to follow through from the preliminary observations in these two cases. Not a particularly comfortable message, but until we know more about the causation of Alzheimer's disease the total reassurance is not practical.

J S METTERS Room 509 Richmond House Pager No: 081-884 3344 Callsign: DOH 832 llllYc!eS 2 92/11.4/1.2

http://collections.europarchive.org/tna/20081106170650/http://www.bseinquiry.gov.uk/files/yb/1992/11/04001001.pdf

>>> The only tenable public line will be that "more research is required’’ <<<

>>> possibility on a transmissible prion remains open<<<

O.K., so it’s about 23 years later, so somebody please tell me, when is "more research is required’’ enough time for evaluation ?

Self-Propagative Replication of Ab Oligomers Suggests Potential Transmissibility in Alzheimer Disease

*** Singeltary comment PLoS ***

Alzheimer’s disease and Transmissible Spongiform Encephalopathy prion disease, Iatrogenic, what if ?

***see Singeltary Comment Posted by flounder on 05 Nov 2014 at 21:27 GMT

http://www.plosone.org/annotation/listThread.action?root=82860

Sunday, November 22, 2015

*** Effect of heating on the stability of amyloid A (AA) fibrils and the intra- and cross-species transmission of AA amyloidosis Abstract

Amyloid A (AA) amyloidosis is a protein misfolding disease characterized by extracellular deposition of AA fibrils. AA fibrils are found in several tissues from food animals with AA amyloidosis. For hygienic purposes, heating is widely used to inactivate microbes in food, but it is uncertain whether heating is sufficient to inactivate AA fibrils and prevent intra- or cross-species transmission. We examined the effect of heating (at 60 °C or 100 °C) and autoclaving (at 121 °C or 135 °C) on murine and bovine AA fibrils using Western blot analysis, transmission electron microscopy (TEM), and mouse model transmission experiments. TEM revealed that a mixture of AA fibrils and amorphous aggregates appeared after heating at 100 °C, whereas autoclaving at 135 °C produced large amorphous aggregates. AA fibrils retained antigen specificity in Western blot analysis when heated at 100 °C or autoclaved at 121 °C, but not when autoclaved at 135 °C. Transmissible pathogenicity of murine and bovine AA fibrils subjected to heating (at 60 °C or 100 °C) was significantly stimulated and resulted in amyloid deposition in mice. Autoclaving of murine AA fibrils at 121 °C or 135 °C significantly decreased amyloid deposition. Moreover, amyloid deposition in mice injected with murine AA fibrils was more severe than that in mice injected with bovine AA fibrils. Bovine AA fibrils autoclaved at 121 °C or 135 °C did not induce amyloid deposition in mice. These results suggest that AA fibrils are relatively heat stable and that similar to prions, autoclaving at 135 °C is required to destroy the pathogenicity of AA fibrils. These findings may contribute to the prevention of AA fibril transmission through food materials to different animals and especially to humans.

Purchase options Price * Issue Purchase USD 511.00 Article Purchase USD 54.00

http://www.tandfonline.com/doi/abs/10.3109/13506129.2015.1095735?journalCode=iamy20

http://betaamyloidcjd.blogspot.com/2015/11/effect-of-heating-on-stability-of.html

Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery.

Gibbs CJ Jr, Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC. Laboratory of Central Nervous System Studies, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.

Stereotactic multicontact electrodes used to probe the cerebral cortex of a middle aged woman with progressive dementia were previously implicated in the accidental transmission of Creutzfeldt-Jakob disease (CJD) to two younger patients. The diagnoses of CJD have been confirmed for all three cases. More than two years after their last use in humans, after three cleanings and repeated sterilisation in ethanol and formaldehyde vapour, the electrodes were implanted in the cortex of a chimpanzee. Eighteen months later the animal became ill with CJD. This finding serves to re-emphasise the potential danger posed by reuse of instruments contaminated with the agents of spongiform encephalopathies, even after scrupulous attempts to clean them.

http://www.ncbi.nlm.nih.gov/entrez/query...p;dopt=Abstract

Saturday, February 6, 2016

*** Secretary's Advisory Committee on Animal Health; Meeting [Docket No. APHIS-2016-0007] Singeltary Submission ***

http://animalhealthreportpriontse.blogspot.com/2016/02/secretarys-advisory-committee-on-animal.html


sad...terry



Originally Posted By: Pitchfork Predator
Originally Posted By: flounder
we must test in higher numbers across the board, and until a validated cwd test for cervid is approved that is 100% accurate, you are going to have to use the scorched earth policy to do that, like it or not. it's the only way to date. it ain't pretty. but do we all want to leave a legacy of drooling stumbling sick cervid with cwd mad deer disease tse prion for our children ? I don't think so. ...


this just out ;


Friday, February 05, 2016

TEXAS NEW CHRONIC WASTING DISEASE CWD CASE DISCOVERD AT CAPTIVE DEER RELEASE SITE

http://chronic-wasting-disease.blogspot.com/2016/02/texas-new-chronic-wasting-disease-cwd.html



Friday, February 05, 2016

Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild

http://chronic-wasting-disease.blogspot.com/2016/02/report-of-committee-on-wildlife.html


kind regards, terry


So is this the way you would treat people if you were their doctor and they had Alzheimers disease?

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#6172864 - 02/07/16 10:31 AM Re: Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION Detections in Farmed Cervids and Wild [Re: flounder]
jmh004 Online   content
Bird Dog

Registered: 10/01/14
Posts: 387
Interesting how flounder will reply on Alzheimer's with a post as long as War & Peace, but can't reply at all about how many deer HE submitted for testing. Always has the same "fix" for CWD, must kill everything blah blah blah. We get it, we got it. Thank you for your input.

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