I have both and for pistol the Dillon 650 is hard to beat and i would give it the advantage. For rifle I like the Hornady OK and the Hornady is easier to swap calibers on too.
The Dillon is so easy and cranks out rounds so fast I don't get to use it much as I don't shoot enough pistol to keep it busy.
"Anyone taking up handloading necessarily plays with unknown factors and takes chances. But so does anyone who drives a car,goes to a cocktail party,eats in a restaurant,or gets married."
Jack O'Connor 1963