1). Lighter suppressors are usually less durable and always more comfortable.
2). 7.62 suppressors usually work just as well as 5.56 suppressors on 5.56 rifles.
3). 7.62 suppressors are almost always significantly heavier than 5.56 suppressors.
4). For the most part, precision shooters prefer direct thread suppressors.
5). Stainless steel is more durable than titanium for rapid fire, etc.
All this really means is that there's no one suppressor that's best for everything. You must decide what's most important to you. Light weight, durability, convenient use on multiple firearms, convenient use on multiple calibers, muzzle brake support, etc.
If you're unsure of exactly what you want, the Liberty Mystic X is a Swiss Army knife suppressor, that you can use on .22 RF, 9mm pistol, .300 BO rifle and 5.56 rifle. A direct thread YHM Phantom 7.62 is heavy and a previous generation design; it's also comparatively inexpensive and virtually indestructible.
I have, and greatly like a SilencerCo Specwar 7.62, but I also subsequently ordered the lightweight Specwar K for my 5.56 carbines, as the 7.62 unit is simply too much of a good thing. Many like the SilencerCo Saker and others find the Omega preferable for use on bolt action hunting rifles; I've got a direct thread Griffin Sportsman on the way for that use.
You might want to watch some of the demo videos on the Silencer Shop web site or on YouTube. My only suggestion is that you avoid companies known to have mediocre customer service and/or poor quality.
A final suggestion: everyone says that a .22 suppressor is a must-have. Guess what? They're right. It will put a grin on your face like few other things, so strongly consider ordering a .22 suppressor in addition to the larger unit.
NRA Endowment & DSC Lifer