Doc, I am shooting 6.5 Grendel, Hornady SST 123 gr. factory ammo. It does a really nice job at penetration. I got the tape measure out and measure the distance from the entry wound to the broken humerus and it was right at 16" which is pretty good considering how much bone was undoubtedly hit along the way.
Somewhere, a true believer is training to kill you. He doesn't care about time, comfort, or mercy. He only knows the Cause, and that it's his home. He will not tire, slow, or quit until he wins. Are you prepared to fight him? Are you prepared to win?